Vetverbranding

Het ADIPOQ gen bevat de informatie die nodig is om het hormoon adiponectine te produceren dat betrokken is bij het stimuleren van de stofwisseling, het afbreken van vetten en het reguleren van glucoseconcentraties in het bloed. Lagere adiponectinespiegels worden geassocieerd met insulineweerstand, een verhoogde BMI en grotere hoeveelheden vet rond de buikstreek. Dit kan leiden tot obesitas en andere obesitas-gerelateerde aandoeningen. De adiponectinespiegels nemen toe met gewichtsverlies en nemen af ​​met gewichtstoename.

  • Gao M, Ding D, Huang J, Qu Y, Wang Y, Huang Q. Association of genetic variants in the adiponectin gene with metabolic
    syndrome: a case-control study and a systematic meta-analysis in the Chinese population. PLoS One 2013; 8(4): e58412.
  • Hara K, Boutin P, Mori Y, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002; 51(2): 536-40.
  • Lu JF, Zhou Y, Huang GH, Jiang HX, Hu BL, Qin SY. Association of ADIPOQ polymorphisms with obesity risk: a meta-analysis. Hum Immunol 2014; 75(10): 1062-8.
  • Shin MJ, Jang Y, Koh SJ, et al. The association of SNP276G>T at adiponectin gene with circulating adiponectin and insulin resistance in response to mild weight loss. Int J Obes (Lond) 2006; 30(12): 1702-8.
  • Mente A, Razak F, Blankenberg S, et al. Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care 2010; 33(7): 1629-34.
  • Cheung CY, Hui EY, Cheung BM, et al. Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study. Eur J Endocrinol 2014; 171(1): 107-15.
  • Reis CE, Bressan J, Alfenas RC. Effect of the diet components on adiponectin levels. Nutr Hosp 2010; 25(6): 881-8.
  • Yu N, Ruan Y, Gao X, Sun J. Systematic Review and Meta-Analysis of Randomized, Controlled Trials on the Effect of Exercise on Serum Leptin and Adiponectin in Overweight and Obese Individuals. Horm Metab Res 2017; 49(3): 164-73.